Evaluation of epigenetic changes of liver tissue induced by oral administration of Titanium dioxide nanoparticles and possible protective role of Nigella Sativa oil, in adult male albino rats
Objective (s): Titanium dioxide nanoparticles (TiO2 NPs) have been recognized as biologically inert material and have been used in a multitude of applications.Nevertheless, the negative impact on the human health is not yet well understood.Aim of the work: The Washbag study attempted to evaluate the epigenetic changes of the genome, in the form of